EPITARGET
EPITARGET
EPITARGET

Project Coordinator - Lund University

Merab Kokaia

 Lund University

Prof. Mérab Kokaia

Coordinator

Phone: +46 46 2220547

Fax: +46 46 2220560

undefinedE-Mail

 

undefinedPubMed

undefinedResearchGate

Lunds Universitet

Paradisgatan 2

22100 Lund

Sweden

undefinedWebsite

EPITARGET Team ULUND

Christine Ekdahl Esbjörn Melin

Christine Ekdahl, MD PhD

PI Inflammation and Stem Cell Therapy Group

Phone: +46 46 2220550

Fax: +46 46 2220550

undefinedE-Mail

Esbjörn Melin

PhD student

Phone: +46 46 2220551

undefinedE-Mail

Una Avdic Jenny Wickham

Una Avdic

Pre-PhD student

Phone: +46 46 2220551

undefinedE-Mail

Jenny Wickham

PhD student

Phone: +46 46 2220552

undefinedE-Mail

Tania Ramos Moreno Idrish Ali

Tania Ramos Moreno, PhD

Post doc

Phone: +46 46 2220551

undefinedE-Mail

Idrish Ali, PhD

Post doc

Phone: +46 46 2220550

undefinedE-Mail

Deepti Chugh Susanne Jonsson

Deepti Chugh

PhD student

Phone: +46 46 2220550

undefinedE-Mail

Susanne Jonsson

Biomedical scientist

Phone: +46 46 2220550

undefinedE-Mail

Magnus Zätterström Mirja Carlsson Möller

Magnus Zätterström

Economist

Phone: +46 46 222 81 44

undefinedE-Mail

Mirja Carlsson Möller

Grant Manager

Phone: +46 46 222 0548

undefinedE-Mail

Institute Presentation

undefinedUniversity of Lund is one of the leading neuroscience research centers in Sweden. Here, Lund University is represented by the newly established undefinedEpilepsy Center, a unique epilepsy research center in Sweden, where strong basic, preclinical and clinical epilepsy research is concentrated. Main research areas of the Center are mechanisms of epileptogenesis and ictogenesis, as well as exploring and developing novel treatment strategies for epilepsy, based on optogenetic approach, immunomodulation, and gene and stem cell therapies. The role of adult neurogenesis in epileptogenesis is also one of the main research topics of the Center. The Epilepsy Center is located within Lund University Biomedical Center (undefinedBMC), where neighbouring research groups explore other neurological diseases, such as neurodegenerative diseases, stroke, and depression. This creates a highly dynamic and scientifically stimulating environment, promoting close interaction and exchange of frontier research and ideas between scientists and students from different fields through common seminars and workshops. Epilepsy Center also has close collaborations with NeuroNano Research Center in Lund. Members of Epilepsy Center possess or have access to a wide range of methodological facilities, including advanced electrophysiological set-ups for patch-clamping, electrical kindling and SE sets of equipment, wireless video-EEG monitoring systems, confocal and 2-photon microscope, cell and brain slice culturing, established logistical solutions for electrophysiological recording from human surgically resected (from mTLE patients) brain slices (including patch-clam recordings), immunostainings, ELISA, Western blots, access to small animal 9.4 Tesla MRI and microPET imaging, viral vector production core and injection room (P2 level), etc. All this expertise and facilities are highly relevant to the project.

 

Professor Mérab Kokaia has many years of experience in epilepsy research, with a main interest in mechanisms of epileptogenesis and ictogenesis, particularly in exploring and developing novel treatment strategies based on optogenetics, gene and stem cell therapies. Prof. Kokaia has contributed to the epilepsy field by several major discoveries, among which the crucial role of neurotrophins in epileptogenesis, inhibition of epileptogenesis by cell transplantation, and, most recently, suppression of epileptifrom activity by optogenetic strategies could be mentioned.

Christine Ekdahl Clementson, MD PhD, is one of the leading researchers in the field of inflammation and neurogenesis in epilepsy. Her group is currently focused on the role of synaptic proteins, inflammation and neurogenesis as potential biomarkers and targets for therapeutic intervention in epilepsy. University of Lund have also contributed substantially to the stem cell field by discovering increased neurogenesis after epileptic seizures, and by exploring functional integration of newly born neurons into the epileptic tissue circuitry.

EPITARGET Team

EPITARGET Consortium
 

EPITARGET Workpackages

EPITARGET Workpackages

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