EPITARGET
EPITARGET
EPITARGET

Partner 4 - University of Eastern Finland

Asla Pitkänen

University of Eastern Finland

Prof. Asla Pitkänen

Principal Investigator

Phone: +358 505172091

Fax: +358 17163025

undefinedE-Mail

 

undefinedPubMed

undefinedResearchGate

University of Eastern Finland - ITÄ-SUOMEN YLIOPISTO

Yliopistonranta 1E

70211 Kuopio

Finland

undefinedWebsite

Team Pitkänen laboratory

Diana Miszczuk, PhD           

Postdoctoral fellow

Phone: +358 403553668

Fax: +358 17163025

undefinedE-Mail

Jarmo Hartikainen

Technician/preclinical laboratory experiments

Phone: +358 403553236

Fax: +358 17163025

undefinedE-Mail

Niina Lapinlampi, BSc

Researcher, REDCap Manager

Phone: +358 403553670

undefinedE-Mail

Team Gröhn laboratory

Olli Gröhn

Prof. Olli Gröhn

Professor of biomedical imaging/Preclinical Imaging

Phone: +358 50 3590963

Fax: +358 17163030

undefinedE-Mail

Team Leinonen laboratory

Ville Leinonen

Assistant Prof. Ville Leinonen

Neurosurgeon

Phone: +358 447172303

Fax: +358 17173916

undefinedE-Mail

Dr Olli-Pekka Kämäräinen

Tissue sampling

Dr Jukka  Huttunen

Tissue sampling

Marita Voutilainen

Research Nurse / Handling the samples and clinical data

Institute presentation

undefinedUEF (Pitkänen and Gröhn) is the 3rd largest University in Finland with about 15 000 students. The A. I. Virtanen Institute (undefinedAIVI) for Molecular Sciences, a Research Institute at the Faculty of Health in UEF, harbours 240 scientists (12 group leaders). AIVI is equipped with modern histology, molecular biology, and imaging laboratories, including biomedical imaging unit contributing to EPITARGET, equipped with three high field MRI systems, SPECT/mCT, IVIS optical imaging, multiphoton and ultrasound imaging. State-of-the art animal facilities have devices for induction of status epilepticus and traumatic brain injury. Video-EEG monitoring units and analysis software are available for monitoring of 50 animals at a time. Behavioural testing setups are available for analysis of motor, sensory, memory and neuropsychiatric functions in rodents. Kuopio University Hospital (undefinedKUH) (Leinonen) is located about 0.5 km from the UEF. The Department of Neurosurgery serves a population of 850 000 in Eastern Finland performing 2000 neurosurgical procedures every year, including over 100 TBI patients. Diagnostic brain biopsies to evaluate neurodegenerative changes in patients with suspected normal pressure hydrocephalus have been done as a routine practice since 1991, and methodology using snap-frozen brain samples (to be used in EPITARGET) since 2010.

Prof. Asla Pitkänen, MD, PhD, DSc, has published over 200 peer‐reviewed papers in journals including PNAS, Brain, Ann Neurol, Lancet Neurology and J Neuroscience. She has worked with animal models of epilepsy since 1982, and conducted several preclinical trials with major pharmaceutical companies. Pitkänen's recent publication activity includes molecular and microstructural analysis of epileptogenesis using state-of-the art molecular and MRI techniques. She has experience in coordinating several research consortia, including FP6 EPICURE (WP coordinator with 4 PIs), ESF project EpiGENet coordinator (6 PIs), and UEF-Brain spear project coordinator (16 PIs).

Prof. Olli Gröhn, PhD, is the director of the National bio-NMR facility and Biomedical Imaging Unit. He has together with his research group focused on the development of novel MRI methodologies, and has utilized those to identify novel non-invasive imaging biomarkers for progressive brain diseases.

Dr. Ville Leinonen, MD, PhD, neurosurgeon, works in the Kuopio University Hospital. He is the director of Kuopio Neurosurgery undefinedNPH (normal pressure hydrocephalus) and Early AD (Alzheimer’s disease) Group, which focus on molecular biology of neurodegeneration in brain biopsies. He has published 30 articles in international scientific journals, including PNAS, Annals of Neurology, Neurology, and Acta Neuropathologica.

EPITARGET Team

EPITARGET Consortium
 

EPITARGET Workpackages

EPITARGET Workpackages

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